Workshop in Bonn

April 4 and 5 at Centro Hotel Bristol Bonn

Workshop Bonn 2019

Agenda Disease Progression Modeling Workshop

In the following agenda, you will find for each talk a link refering to

  • the slide presentation (PDF)
  • the talk in a video


Day 1 – April 4th, 2019:

Biomarker - driven progression models in neurodegenerative diseases (AD, PD)

09:00 Welcome Coffee & Registration
10:00 Martin Hofmann-Apitius
Welcome and setting the stage
10:30 Holger Fröhlich
Modeling of Neurodegenerative Disease Risk and Progression
11:00 Colin Birkenbihl
Validation of risk models for AD using independent progression cohort studies
11:30 Coffee break
12:00 Bertram Müller-Myhsock
Longitudinal modeling and analysis of psychiatry cohort data
12:30 Stanley Durrleman
Longitudinal progression modeling of AD integrating multiscale biomarker data and events
13:00 Alejo Nevado-Holgado
Longitudinal modeling of real-world data: the CRIS data modeling story
13:30 Lunch Break


Digital biomarkers - digital signatures (using wearables and sensors to generate signatures on functional domains)

14:30 Emilio Merlo-Pich
Setting the scene: the RADAR-AD case; motivation and strategy
15:00 Meemansa Sood
Strategies for the alignment of biomarker progression models with digital signatures
15:30 Coffee Break


Visualistics: representation of longitudinal multiscale and multimodal information

16:00 Jörn Kohlhammer
Visual analysis of longitudinal clinical data
16:30 Alex Masny
Semantic integration of multimodal, multiscale (progression) information in VirtualBrainCloud
17:00 Concluding discussion / summary day 1 / preparation for break-out sessions on day 2
18:00 Dinner


Day 2 – April 5th, 2019:
Morning Session: Translational Neuroscience – the bigger picture

08:30 Welcome Coffee
09:00 Martin Hofmann-Apitius
Summary of day 1 and setting the scene for Virtual Cohorts
09:30 Holger Fröhlich
Introducing Longitudinal Virtual Cohorts - a new way of progression modeling, information sharing and simulation
10:00 Coffee break
10:30 - 12:00 Break-out Session

Group A – Salon Bonn I & II
Biomarker progression models and digital biomarkers:
Any change to link them?
How would we use them for e.g. trial simulation?

Group B – Salon Berlin
Perspectives for future pre-competitive collaboration:
What are our next steps?
Where are we going from here?
12:00 Lunch Discussion
13:00 Wrap up, conclusion and closure of meeting
14:00 Departure